Pharma

A new study shows that whether T cell acute lymphoblastic leukemia worsens depends on structural changes in the layout of protein bundles called chromosomes

Recent reports indicate that COVID-19 is already having a negative effect on clinical trials, suggest changes needed to cope

The tuberculosis bacteria induce increased hydrogen sulfide production by human macrophages, which increases pathogenesis

Communities of bacteria known as biofilms are notorious for forming on implanted medical devices and tissues in the body, where they give rise to chronic, sometimes life-threatening infections

Randomized trial shows benefit of belantamab mafodotin in relapsed/refractory patients

Treatment successfully delivers drug across the blood-brain barrier directly to brain tumor in mice

The phase II trial found that over 80 percent of men with prostate cancer whose tumors had mutations in the BRCA genes responded well to treatment with the targeted drug olaparib

By shedding light on several unexpected disease clusters and their costs, this work could inform new approaches for managing chronic conditions

A growing number of patients with advanced lung cancer could soon be offered a blood test to help to decide the best treatment

Study finds that "postprescription audit and review is a feasible and effective strategy for antimicrobial stewardship in settings with limited resources and expertise "