Molecular Biology

Researchers describe a molecular mechanism by which mutations at one site in RNF43 cause cancer—and have also offered a potential method to treat these cancers 

Researchers have developed a statistical model that uses genomic data to predict the risk of developing cancer of the esophagus

Largely ignored molecules expressed in the brain may contribute to imbalances in epilepsy and autism spectrum disorder

A key protein the virus uses to initiate infection does not operate as previously thought, researchers report

A research team has succeeded in developing an RNA molecule that can compensate for the effect of gene mutations in bone marrow cells

Recent study also provides new clues on how to monitor the efficacy of therapy

The new CRISPR-guided DNA base editing technologies are designed to efficiently induce "transversion" alterations of DNA bases while minimizing levels of unwanted "bystander" mutation

Technology combines rapid imaging and machine learning to uncover patterns in how antibacterials kill; can be applied to many pathogens

Not everyone exposed to infectious diarrhea-causing bacteria gets sick

Researchers discovered a small set of microRNAs which were always elevated in epilepsy and designed drug-like molecules, synthesized by chemists from the group, to target these