Immunotherapy

New diagnostic test for MSI in solid tumors can inform physicians on immuno-oncology therapies, and can guide treatment decisions for patients with Lynch-associated cancers

Dana-Farber Cancer Institute scientists have identified several features of kidney cancer tumors that influence their response to immune checkpoint inhibitor drugs

Previous studies have shown that not all patients with metastatic breast cancer benefit from immunotherapy

The largest report of commercial CAR T therapy for lymphoma demonstrates its effectiveness even in patients that would not have been eligible for clinical trials

Researchers have now managed to eliminate leukemic and hematopoietic stem cells more selectively in an animal model, sparing healthy cells and tissues

Approximately 40 percent of melanomas lack sufficient infiltration of immune cells within the tumor and therefore have poor responses to immunotherapies

Researchers recently developed a technique called representative sequencing, which builds a more accurate picture of a tumor's DNA

Immune 'checkpoint' inhibitor treatment found useful against Merkel cell carcinoma in multicenter clinical trial

Study suggests implications for immunotherapy development

Communities of bacteria known as biofilms are notorious for forming on implanted medical devices and tissues in the body, where they give rise to chronic, sometimes life-threatening infections