Genomics

Including participants of diverse ancestries in genome-wide association studies improves disease risk prediction, diagnosis, and development of treatments

New research has identified several genes that appear to drive disease risk at birth, and which could be targeted for therapeutic intervention to stop these diseases

Researchers have been working on improving their ability to identify the genetic cause of undiagnosed conditions

Individualized mosaics of microbial strains transfer from the maternal to the infant gut

Immune checkpoint inhibitors are transforming the field of cancer therapeutics, but their successes are limited by the lack of biomarkers that identify patients most likely to respond

How mass spectrometry, next-generation sequencing, and bioinformatics tools are revolutionizing personalized medicine

CE is a versatile technique for analyzing proteins, DNA, and drug molecules

Tumor heterogeneity may complicate clinical decisions and contribute to drug resistance

Advances in single-cell genomics are resolving cell-type-specific features of pathological conditions

The genomically-adjusted radiation dose (GARD) can predict risk of local tumor recurrence and optimize radiation dose