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Researchers Discover a New Auto-Inflammatory Disease Called CRIA Syndrome
Researchers Discover a New Auto-Inflammatory Disease Called CRIA Syndrome
National Human Genome Research Institute | Jan 9, 2020
Mutations in the RIPK1 gene responsible for CRIA syndrome
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Olaparib Becomes First Gene-Targeted Medicine to Show Benefits in Prostate Cancer
Olaparib Becomes First Gene-Targeted Medicine to Show Benefits in Prostate Cancer
Institute of Cancer Research | Dec 4, 2019
The phase II trial found that over 80 percent of men with prostate cancer whose tumors had mutations in the BRCA genes responded well to treatment with the targeted drug olaparib
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Transient Wave of Hematopoietic Stem Cell Production in Late Fetuses and Young Adults
Transient Wave of Hematopoietic Stem Cell Production in Late Fetuses and Young Adults
Hubrecht Institute | Nov 5, 2019
Researchers have found a previously unappreciated hematopoietic wave taking place in the bone marrow of late fetuses and young adults and producing HSCs from resident hemogenic endothelial cells of somite origin
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New Diagnostic Method Finds Aggressive Tumors
New Diagnostic Method Finds Aggressive Tumors
Karolinska Institutet | Oct 18, 2019
Researchers have developed a new genomic method, named CUTseq, which can assess the amount and type of CNAs in many different parts of the same tumor, at a much lower cost than existing technologies 
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Researchers Identify New Therapeutic Target for Pulmonary Fibrosis
Researchers Identify New Therapeutic Target for Pulmonary Fibrosis
Rockefeller University Press | Oct 10, 2019
The environmental and genetic factors underlying IPF are largely unknown, and there are no effective approaches available to reverse development of the disease
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New CRISPR-Cas9 Variant May Boost Precision in Gene Editing
New CRISPR-Cas9 Variant May Boost Precision in Gene Editing
Karolinska Institutet | Sep 30, 2019
The new variant reduced unintended changes in DNA compared to its wildtype, suggesting it could play a role in gene therapies that require high precision
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Salmonella Causing Bloodstream Infections in Central Africa Resistant to Nearly All Drugs
Salmonella Causing Bloodstream Infections in Central Africa Resistant to Nearly All Drugs
Wellcome Trust Sanger Institute | Sep 6, 2019
A multifaceted approach will be needed to track and control the spread of extensively drug-resistant Salmonella, including further microbiological and genomic surveillance
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BRCA1/2 Genetic Testing Recommendations Still Leave Issues Unresolved
BRCA1/2 Genetic Testing Recommendations Still Leave Issues Unresolved
University of Pennsylvania School of Medicine | Aug 20, 2019
Leaders in BRCA research say screening recommendations from the US Preventive Services Task Force are a positive step forward, but testing of individuals with the highest risk must improve
News
p53 Mutations in 10,000 Cancer Patients Shed New Light on Gene's Function
p53 Mutations in 10,000 Cancer Patients Shed New Light on Gene's Function
Baylor College of Medicine | Jul 31, 2019
Researchers at Baylor College of Medicine have conducted the most comprehensive study of TP53 mutations to better understand the processes leading to the inactivation of this important gene