Novel Complex Cell Manufacturing
Scott D. Hanton, PhD | May 7, 2021
Challenges and critical considerations for the manufacturing of cellular therapies
CAR-T
Protein Critical to T Cells' Antitumor Response Discovered
University of Texas MD Anderson Cancer Center | January 4, 2021
The study suggests that increasing the protein's activity in T cells may enhance the effectiveness of immunotherapy
Genetically Engineered T Cells Could Lead to Therapies for Autoimmune Diseases
University of Arizona Health Sciences | December 4, 2020
The engineered T cells can target and attack pathogenic T cells in a mouse model of Type 1 diabetes
New Immunotherapy Shows Promise Against Rare Childhood Cancer
University College London | November 30, 2020
The study is one of the first to demonstrate CAR T-cells achieving rapid regression against a solid cancer
Novel Dual CAR T Cell Immunotherapy Holds Promise for Targeting the HIV Reservoir
University of Pennsylvania School of Medicine | September 24, 2020
Researchers from Penn, in collaboration with the Ragon Institute, develop a new dual CAR T cell immunotherapy that combats HIV infection in humanized mice
Study Suggests More Could Benefit from CAR T-Cell Therapy
Moffitt Cancer Center | May 14, 2020
The largest report of commercial CAR T therapy for lymphoma demonstrates its effectiveness even in patients that would not have been eligible for clinical trials
Building a Safer CAR-T Therapy
Ludwig Cancer Research | February 4, 2020
A new study addresses a central conundrum of CAR-T therapies: their tendency to provoke potentially deadly runaway immune responses against healthy tissues in patients
Car-T Therapy Improves Outcomes for Patients with B-Cell Lymphoma
University of Chicago Medical Center | December 3, 2018
Forty percent of patients with diffuse large B-cell lymphoma had a complete response, most of which were durable