Study Finds Negligible Detection of Coronavirus in Hematology/Oncology Settings

Study Finds Negligible Detection of Coronavirus in Hematology/Oncology Settings

Researchers found extremely low detection of SARS-CoV-2 on surfaces across multiple outpatient and inpatient areas

Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, evaluated the frequency of SARS-CoV-2, the virus that causes COVID-19, on various environmental surfaces in outpatient and inpatient hematology/oncology settings located within Rutgers Cancer Institute and Robert Wood Johnson University Hospital, an RWJBarnabas Health facility.

"For patients with blood cancers who may be at higher risk of developing complications from the virus, our findings provide a layer of assurance that these patients are safe when frequenting high impact areas where they receive their cancer care."

The study revealed extremely low detection of SARS-CoV-2 on environmental surfaces across multiple outpatient and inpatient oncology areas, including an active COVID-19 floor. Andrew M. Evens, DO, MSc, FACP, associate director for clinical services and director of the Lymphoma Program at Rutgers Cancer Institute and medical director of the oncology service line at RWJBarnabas Health, is senior author of the work, which has been published in the February 18 online edition of Cancer.

Patients harboring hematologic malignancies, which are cancers that affect the blood, bone marrow, and lymph nodes, have demonstrated a potentially higher mortality rate due to the virus. While COVID-19 is transmitted person to person through respiratory droplets, there is a potential risk of SARS-CoV-2 spreading via contact with contaminated surfaces and equipment, especially in health care settings, creating additional concern for patients with blood cancers.

"For patients with blood cancers who may be at higher risk of developing complications from the virus, our findings provide a layer of assurance that these patients are safe when frequenting high impact areas where they receive their cancer care," notes Evens, who is also a professor of medicine at Rutgers Robert Wood Johnson Medical School. "The results of this study help us further understand how COVID-19 is transmitted in hematology/oncology and other medical settings and confirm that strategies like enhanced cleaning and disinfecting policies are extremely effective."


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Environmental swabbing took place in two outpatient clinics including the malignant hematology and medical oncology units and infusion suites, as well as inpatient areas, which included the leukemia/lymphoma/CAR T-cell unit and an inpatient unit caring for patients actively infected with COVID-19. Surfaces were sampled on Mondays, Wednesdays, and Fridays from June 17, 2020, through June 29, 2020. Areas included waiting rooms, infusion areas, bathrooms, floors, elevator banks, doors, and exam rooms, computer equipment, pneumatic tubing stations, pharmacy benches, and medication rooms. Medical equipment was also swabbed from these areas including intravenous poles, chemotherapy bags, vitals monitor, telemetry stations, and linen carts.

"The overall positive test rate for SARS-CoV-2 RNA across all surfaces in the combined outpatient and inpatient hematology/oncology units was a low 0.5 percent."

Analysis of the 130 samples collected were separated into three categories: patient/public areas (85), staff areas (22), and medical equipment (23). In the two outpatient clinics and inpatient leukemia/lymphoma/CAR T-cell unit, no SARS-CoV-2 RNA was detected on any swabbed surfaces. In the inpatient COVID unit, one patient/public sample was positive for detection of SARS-CoV-2 RNA in an area where a patient with recent infection was receiving treatment.

Thus, the overall positive test rate for SARS-CoV-2 RNA across all surfaces in the combined outpatient and inpatient hematology/oncology units was a low 0.5 percent.

The authors note study limitations including the inability to analyze the complete surface area of the varied locations, which may have reduced sensitivity. In addition, researchers did not attempt to culture SARS-CoV-2 from the one positive sample; it is unknown if it contained live virus. Continued studies are needed to monitor rates of virus transmission and the environmental factors involved in the propagation of the SARS-CoV-2 infection.

- This press release was originally published on the Rutgers Today website