Insight

The ultracold storage needs of the Pfizer-BioNTech COVID-19 vaccine compounds the challenges inherent to vaccinating rural populations

mRNA vaccines employ a novel strategy to stimulate immunity against coronavirus spike proteins

To overcome the challenges of NGS, researchers have turned to third-generation or long-read sequencing technologies

The innovative approach combines histopathology and genomics to create maps of genetic expression throughout a tissue

Next-generation sequencing can identify known and novel genetic mutations that underlie complex neurological disorders

Approaches clinical laboratories can take to reduce diagnostic blood loss

With no clear standards for A1C screening in early pregnancy, researchers focus on establishing useful guidelines

Screening for blood cell mutations can identify those at greater risk for hematologic cancers and cardiovascular disease

Promising results from the first in-human trials of genetically engineered malaria vaccines

As new compounds and masking agents continue to emerge, analytical methods must evolve to enable their detection

Recent research reveals a complex interaction between the microbiome and the immune system in pancreatic cancer

Recent evidence suggests procalcitonin tests may be able to identify COVID-19 patients with bacterial coinfections to guide antibiotic treatment

ADME profoundly affects a drug’s properties and has long been a cornerstone of pharmacology and drug discovery

Researchers are using patient-derived tumor organoids to match patients with optimal treatments

Next-generation sequencing has revolutionized the detection of tumor neoantigens

Researchers and regulatory authorities are exploring ways to condense the usual vaccine development timeline

Promising results from the first in-human trials of genetically engineered malaria vaccines

Reproducible workflows would help clinical labs successfully and routinely perform liquid biopsy assays

Early diagnosis is critical, but fraught with challenges including the widespread use of PrEP

Major challenges testing labs face are preventing contamination, keeping up with the demand for testing, and maintaining an efficiency and accuracy