Insight

ADME profoundly affects a drug’s properties and has long been a cornerstone of pharmacology and drug discovery

Researchers are using patient-derived tumor organoids to match patients with optimal treatments

Next-generation sequencing has revolutionized the detection of tumor neoantigens

Researchers and regulatory authorities are exploring ways to condense the usual vaccine development timeline

Promising results from the first in-human trials of genetically engineered malaria vaccines

Reproducible workflows would help clinical labs successfully and routinely perform liquid biopsy assays

Early diagnosis is critical, but fraught with challenges including the widespread use of PrEP

Major challenges testing labs face are preventing contamination, keeping up with the demand for testing, and maintaining an efficiency and accuracy

Mosquito-borne diseases are transmitted when a mosquito ingests viruses, parasites, or bacteria from a host and injects them into another individual

What needs to be done to ensure labs have proper diagnostic tools for future outbreaks

Considerations for labs preparing to develop or run SARS-CoV-2 assays

Reduction of circulating cardiac biomarkers is often associated with improved prognosis, making them potentially useful in therapy guidance

Some labs are limiting their testing due to the shortages, while others are getting creative

Often referred to as an "invisible illness," endometriosis remains poorly understood

Choosing the right test for the right situation can lead to more effective control of the virus

Urine culture is the gold standard, but labs can accelerate detection by using molecular methods

Lack of materials needed to conduct tests gave labs a slow start

How pathogens have shaped our history

Labs have expanded their efforts, but testing in the US continues to lag

Diagnostic tests for COVID-19 have evolved rapidly since the earliest cases